Efek Kombinasi Ramuan Jamu Terhadap Tekanan Darah dan Kolesterol Pasien di Rumah Riset Jamu Hortus Medicus:

The Effect of Combination of Jamu Formulaon Blood Pressure and Cholesterol of Patients in Hortus Medicus Jamu Research Center

Abstract

Hipertensi dan hiperkolesterolemia masih merupakan masalah di bidang kesehatan. Penanganan pasien hipertensi yang disertai hiperkolesterolemia memerlukan perhatian khusus. Di Rumah Riset Jamu (RRJ) terdapat banyak pasien hipertensi dengan hiperkolesterolemia yang diterapi menggunakan kombinasi ramuan jamu antihipertensi dan antihiperkolesterolemia. Penelitian ini bertujuan untuk mengetahui efek kombinasi ramuan jamu tersebut dalam menurunkan tekanan darah dan kadar kolesterol. Penelitian ini dilakukan menggunakan metode kohort retrospektif. Sampel didapatkan dari data rekam medik pasien hipertensi yang disertai hiperkolesterolemia di RRJ Hortus Medicus tahun 2017. Subjek penelitian ini adalah pasien yang berusia 20-65 tahun dan telah menjalani terapi kombinasi ramuan jamu antihipertensi dan antihiperkolesterol minimal 28 hari. Analisis dilakukan dengan membandingkan tekanan darah dan kadar kolesterol pasien pada hari ke-0 dan hari ke-28 masing-masing menggunakan uji t berpasangan. Sebanyak 223 data pasien didapatkan. Setelah 28 hari, terdapat 74 orang yang berhasil mencapai tekanan darah normal dan 115 orang berhasil mencapai kadar kolesterol normal. Tekanan darah sistolik berbeda secara signifikan antara sebelum dan setelah pemberian ramuan jamu, p=0,000. Demikian juga tekanan darah diastolik berbeda secara signifikan antara sebelum dan setelah pemberian ramuan jamu p=0,005. Kadar kolesterol di dalam darah pasien juga berbeda secara signifikan antara sebelum dan setelah pemberian ramuan jamu, p=0,014. Berdasarkan hasil di atas, dapat disimpulkan bahwa pemberian kombinasi ramuan jamu antihipertensi dan antihiperkolesterolemia selama 28 hari dapat menurunkan tekanan darah dan kadar kolesterol pasien secara signifikan.

Hypertension and hypercholesterolemia are still a health problem. Treatment of hypertensive patients comorbid with hypercholesterolemia requires special attention. At the Jamu Research House (RRJ) there are many hypertensive patients with hypercholesterolemia who are treated using a combination of antihypertensive and antihypercholesterolemic herbs. This study aimed to determine the effect of the combination of jamu in lowering blood pressure and cholesterol levels. This study was conducted using a retrospective cohort method. Samples were obtained from medical record of hypertensive patients comorbid with hypercholesterolemia at RRJ Hortus Medicines in 2017. The subjects of this study were patients aged 20-65 years and had undergone a combination therapy of antihypertensive and antihypercholesterolemicjamu at least 28 days. The analysis was carried out by comparing the blood pressure and cholesterol levels of patients on day 0 and day 28 using paired t test. A number of 223 patient data were obtained. After 28 days, there were 74 people who reach normal blood pressure and 115 people achieve normal cholesterol levels. Systolic blood pressure was significantly different between before and after the administration of jamu, p = 0,000. Likewise, diastolic blood pressure was significantly different between before and after the administration of jamu with p = 0.005. Cholesterol levels in the patient's blood also differed significantly between before and after administration of jamu formula, p = 0.014. Based on the above results, it can be concluded that the combination of antihypertensive and antihypercholesterolemic jamu for 28 days significantly reduced blood pressure and patient cholesterol levels